| HTC | 2006– | The main smartphone brand (before 2006, OEM only) |
| Qtek | 2004–2006 | HTC's own brand for Europe via the distributor Brightstar; wound down when HTC moved to its own brand |
| Dopod (多普達) | 2005–2008 | An acquired Asian brand (Taiwan, China, Southeast Asia); merged into HTC |
| HTC VIVE | 2015– | VR/XR headsets, trackers, software |
| VIVEPORT | 2016– | VR app store and the Infinity subscription |
| Vive X | 2017– | Accelerator for VR/AR startups |
| Vive Studios | 2016– | Game and content studio |
| Vive Arts | 2017– | Projects with museums |
| VIVERSE | 2022– | Metaverse platform, 3D streaming |
| G REIGNS (鴻鵠國際) | 2020– | Subsidiary: private 5G networks, O-RAN, modems for Taiwan and Asia |
| DeepQ | 2016– | Medical AI (the Lily chatbot, educational AI), a subsidiary |
| HTC Exodus | 2018–2020 | Blockchain smartphones and the Zion wallet |
| Beats Electronics | 2011–2013 (stake 50.1%→25%) | Headphones; HTC exited the equity before Apple's purchase |
| S3 Graphics | 2011– | Bought from VIA for $300 million for its patents (it did not help in the suit against Apple) |
| HTC Creative Labs / Magic Labs | 2007–2015 | Internal R&D labs |
| HTC One Design Studio | 2008–2015 | Design studio in San Francisco (Scott Croyle) |
| Saffron Digital | 2011–2014 | A London video platform, sold to Amdocs |
| Dashwire | 2011 | Cloud sync, acquired |
| Inquisitive Minds (Zoodles) | 2012 | Kids' apps |
| OnLive | 2011 | A $40 million investment in cloud gaming, written off |